The seismic behavior of modern composite structures, particularly those utilizing concrete-filled steel tube columns (CFST) and concrete-filled double steel tube columns (CFDST), is under scrutiny due to the increasing risk posed by earthquakes, especially in regions along the Pacific Ring of Fire and areas in Central Europe like Germany. As megacities develop in these high-seismic zones, understanding the performance of innovative materials and designs is crucial. Recent research highlights that CFST and CFDST columns exhibit superior load-bearing capacity, deformation capacity, and energy dissipation, making them advantageous in seismic applications compared to traditional high-strength reinforced concrete columns. However, the effective application of these composite columns in high-rise and industrial buildings necessitates experimental validation of their performance under seismic loads. Our current projects focus on evaluating the seismic behavior of moment-resisting frames (MRFs) constructed with these columns, exploring factors such as system reduction effects and frame interactions that influence overall structural integrity. Experimental tests combined with advanced finite element modeling aim to better understand the interactions and failure mechanisms of composite structures during seismic events, thus enhancing the design and safety of future buildings in earthquake-prone areas.